WHAT IS IUI?
Intrauterine Insemination (IUI) involves a laboratory procedure to separate fast-moving sperm from more sluggish or non-moving sperm. Sperm produced by masturbation are separated in the laboratory and are then placed into the woman’s uterus close to the time of ovulation when the egg is released from the ovary.
This treatment may be offered to improve the chance of conception if sperm quality is slightly low. It is not appropriate for cases when sperm quality is poor. The procedure is also not recommended when the fallopian tubes are damaged.
Tubal patency tests
Fallopian tubes should be open and healthy before the IUI process begins. A tubal patency test is usually carried out as part of your assessment either by hysterosalpingogram (HSG) or by a laparoscopy. The recommended method for assessing the patency of your Fallopian tubes is laparoscopy and dye testing. When the pelvis and tubes are healthy, dye passes freely through both tubes. There should also be no adhesions present that might prevent an egg from having access to either tube from the ovaries. Tests may show that you have only one open healthy Fallopian tube, although you may have both ovaries. If so, IUI treatment can only be carried out when there is evidence that ovulation is about to occur from the ovary that is on the same side as the healthy tube. This does not give good results You may also offer to undergo an HSG Hysterosalpingo- Contrast Sonography (HyCoSy) – an ultrasound examination to check the uterine cavity and the patency of Fallopian tubes or an HSG(Hysterosalpingogram).
IUI with or without fertility drugs
IUI can be given with or without fertility drugs to boost egg production after assessing the individual case.
How does IUI work?
If you are not using fertility drugs, IUI is carried out between day 12 and day 16 of your monthly cycle – with day one being the first day of your period. We may ask that you carry out testing yourself using an ovulation predictor kit to detect the hormone surge that signals imminent ovulation. Doctor will offer scan monitoring to make the timing of insemination more accurate.
Alternatively, if we recommend that you use fertility drugs to stimulate ovulation, vaginal ultrasound scans will be used to track the development of your eggs. As soon as an egg is mature, you will be given a hormone injection (Ovitrelle/ Pregnyl) to stimulate its release.
The sperm will be inseminated 24 to 36 hours after your ovulation. The procedure is very similar to having a smear test with a speculum. A small catheter (a soft, flexible tube) is then threaded into your womb via your cervix. A prepared sperm sample, containing the best quality sperm, is inserted through the catheter. The whole process takes just a few minutes and is usually painless but some women may experience temporary menstrual-like cramping. Following the procedure, we may recommend that you rest for 15-20 minutes before going home. The entire procedure is witnessed by at least two professionals to ensure that right sperm is inseminated in the right patient.
Success rates of IUI
The success rates of IUI depend on the woman’s age at the time of treatment. The clinical pregnancy rate in women aged 36 or less is between 10-12% per treatment cycle.
In the event of three (or less, depending on your situation) unsuccessful IUI cycles, we would advise you to have a consultation to discuss other treatment options.
You will be asked to produce a sperm sample on the day of the treatment. Your sperm will be washed to remove the fluid surrounding them and to separate the rapidly moving, best sperm, from the rest of your sample. The rapidly Moving sperm are then placed in a small catheter (tube) to be inserted into the woman’s uterus
IUI with partner’s sperm or donor sperm If your partner is unable to provide sperm, or if you do not have a male partner, you may wish to consider using donated sperm.
The risks of IUI
The biggest risk associated with stimulated IUI is the risk of multiple births and sometimes ovarian hyperstimulation.
Intrauterine insemination is a procedure where semen sample is collected & processed in the laboratory using swim up or double density gradient method, using media and good quality robust sperms are injected into the uterine cavity around the time ovulation.
- Cervical factor infertility
- Unexplained infertility
- Minimal endometriosis
- Oligospermia ( minimal)
- Donar insemination, semen cryo,
- Preservation and semen banking facilities available here.
Chances of infection.